Friday, January 22, 2010

Penetration


The next step in the virus replication cycle after the attachment is penetration. Penetration is the process by which the virus goes into the plasma membrane and prepare for is uncoating. Penetration of eukaryotic cells occurs in three ways.

The first way is the Receptor-mediated (enveloped-virus). It is a process by which cells internalize molecules by the inward budding cell membrane vesicles containing proteins with receptor sites specific to the molecules being internalize.

The virus binds to its specific receptor and goes into the plasma membrane.

The function of the receptor-mediated endocytosis is used for the specific uptake of certain substance required by cell.

Clathrin is another way for the penetration. Though both receptor mediated and clathrin are almost the same, clathrin usually occur for naked viruses whereas receptor mediated are for enveloped viruses.

The last one would be the fusion of enveloped virus. It is said to be a direct penetration method.

I'll end here for penetration. Enjoy!

1 comment:

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