Maturation
The stage of the life-cycle at which the virus becomes infectious. Usually involves structural changes in the particle, often resulting from specific cleavage of capsid proteins to form the mature products, which frequently leads to a conformational change in the capsid, or the condensation of nucleoproteins with the genome. For some viruses, assembly and maturation are inseparable, whereas for others, maturation may occur after the virus particle has left the cell.
The stage of the life-cycle at which the virus becomes infectious. Usually involves structural changes in the particle, often resulting from specific cleavage of capsid proteins to form the mature products, which frequently leads to a conformational change in the capsid, or the condensation of nucleoproteins with the genome. For some viruses, assembly and maturation are inseparable, whereas for others, maturation may occur after the virus particle has left the cell.
Generally, protein capsid is assembled around the viral genome
Fig. 1A: Maturation of an Enveloped Virus
Envelope glycoproteins are transported to the host cell's cytoplasmic membrane and the capsid assembles around the viral genome.
Fig. 1B: Maturation of a Naked Virus
The capsid assembles around the viral genome.
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